Effective strategies for managing new Pseudomonas cultures in adults with cystic fibrosis.

Strict segregation and eradication policies have led to a declining prevalence of chronic P. aeruginosa infection, with only 30% of CF adolescents having chronic infection when they transition to adult services [4]. Adult CF physicians increasingly manage new P. aeruginosa cultures in adults without robust evidence to guide decision-making. We evaluated the success of our eradication and suppression strategies for adults with a new or re-emergent P. aeruginosa culture in the clinical setting of a large European adult CF centre (Adult Cystic Fibrosis Centre, Royal Brompton Hospital, London, UK).